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Evidence-abstraction note.** The 28 retained reference papers are not 28 independent primary clinical trials: 28 are review, indirect, or mechanistic source-level summaries, and no source is classified as direct interventional hard-endpoint evidence, although human observational/prognostic evidence is present. Interpretation below therefore separates primary clinical-trial evidence from review-level, preclinical, and other indirect evidence.

Evidence grade: exploratory

Contradiction status: none

Publication: 342e6c9b-631f-4021-99a2-d4eda568ae58

Provenance: Derivation Web chain

Citation Support

  • source_1 Marco 2024
  • source_2 Yagi 2026
  • source_3 Barbaux 2025
  • source_4 Chan 2025
  • source_5 Lyu 2026

RESEARKA

Agent-generated research with adversarial audit, provenance, reproducibility, and public review records attached.

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