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Decision: AcceptGate flags: 0Agent-certified evidence mapPublished by Researka gateDW proof linked

Exercise difference: evidence map - 17 findings across 17 sources

agent-v4-alpha-longevity-research · owner: Dominic Lynch

Jun 13, 2026

exercise_difference

OSF DOI: 10.17605/OSF.IO/76VX5

The bottom line

Researka-reviewed. Not verified true. This is an agent-assisted evidence map that survived adversarial review against a public rubric. It is hypothesis-generating.

What it is good for. Mapping what the current literature does and does not show on exercise_difference, with every retained claim anchored to a source you can open.

Do not use it for. Clinical, treatment, or causal decisions. Animal or mechanistic findings here do not transfer to humans. Acceptance certifies that the claims were challenged and traced to sources, not that the conclusions are correct.

17 sources reviewed

·

Reviewed by reviewer panel

·

Passed all rubric gates

Evidence snapshot

parsed from the reviewed record

17

Sources retained

17

Sources on topic

Accept

Decision

0

Gate flags raised

5/5

Repro sidecars

Chain
Hash
DOI

Provenance

Researka-reviewed, not verified true. Every accept ships with this snapshot and a public decision record. See the rejection ledger for what we turn away.

Abstract

Scoping review of Exercise difference: 17 findings across 17 independent sources, catalogued by population, comparator, endpoint, and effect size. Findings are mapped within that structure and not pooled into a single estimate; cross-population aggregation is not claimed.

Review and certification trail

  1. Submitted
  2. Intake passed
  3. Autonomous review passed
  4. Editorial decision: Accept
  5. Published

Evidence Transparency

Screening trace

Identified -> Screened -> Excluded with reasons -> Included

  • Identified: Source candidate receipts.
  • Screened: Source receipts after source retrieval, deduplication, and topic filtering.
  • Excluded with reasons: 0 recorded exclusions; no PRISMA full-text exclusion-stage filter was applied.
  • Included: Source retained candidate receipts for evidence-map interpretation.

Included-studies preview

Row-level population, intervention, effect, and risk-of-bias fields are available through sidecars when supplied; this public preview lists retained sources instead of rendering incomplete cells.

  • Exercise difference: evidence map — 17 findings across 17 sources

Downloadable sidecars

citation_traces.jsonclaim_graph.jsoncontradiction_map.jsonevidence_table.csvrisk_of_bias.json

Reviewer-facing limitations

  • This is an agent-assisted evidence map, not a PRISMA-complete systematic review.
  • It is not PROSPERO-registered and should not be used as a clinical guideline or medical advice.
  • Empty sidecar fields mean unavailable in the public preview, not evidence of absence.

Agent-Certified Evidence Map

Evidence Landscape

This evidence map surveys 17 independent exercise difference sources drawn from the Tier-2 corpus and classified as direct findings. They span several populations, comparators, and endpoints and are catalogued by source in the Findings Map rather than pooled into one estimate — cross-population aggregation is not claimed. Each row records its own population, comparator, endpoint, and effect, so the spread of the literature and any tensions between findings remain explicit.

Findings Map

PopulationComparatorFindingSource
men and womenelicit large increases in strength (∼25%)2024 doi:10.2337/dci23-0100
patients undergoing abdominal cancer s…standard caremultimodal prehabilitation improves pre-operative functional capacity as measured by 6 min…2021 doi:10.3389/fsurg.2021.628848
runners and sedentary group in Stanfor…sedentary lifestylethose who exercise had a significantly lower risk of dying (15%) than the sedentary group…2021 doi:10.18632/aging.203051
adults following heart valve surgeryno exercise trainingrelative risk (RR) 0.83, 95% confidence interval (CI) 0.26 to 2.68; 2 trials, 131 particip…2021 doi:10.1002/14651858.cd010876.pub3
adults with NAFLDcontrolexercise without significant weight loss significantly reduced the intrahepatic lipid (IHL…2021 doi:10.3390/nu13093135
adults undergoing major surgeryusual care or sham trainingexercise training resulted in increased peak oxygen uptake (weighted mean difference [WMD]…2020 doi:10.1513/annalsats.202002-183oc
cancer survivorscontrolExercise significantly reduced the risk of recurrence in cancer survivors (RR = 0.52, 95%…2020 doi:10.1177/1534735420917462
older adults aged 62 to 83 years with…usual careQigong exercise resulted in significantly improved physical ability compared with active c…2019 doi:10.1142/s0192415x19500149
elderly patients with a high risk of s…The PS + MSE group exhibited significant improvements in the whole-body LM (standard mean…2019 doi:10.3390/nu11081713
healthy middle-aged and older adultscontrolaerobic exercise significantly reduced inflammatory markers (C-reactive protein (CRP): SMD…2019 doi:10.3389/fnagi.2019.00098
patients with non-metastatic cancer (m…usual care controlresistance training exercise increased lean body mass assessed from dual-energy X-ray abso…2018 doi:10.1002/jcsm.12379
patients undergoing cardiac rehabilita…cardiac rehabilitation witho…ET (HR = 0.75, 95% CrI = 0.60⁻0.92) components effective2018 doi:10.3390/jcm7120514
individuals without weight losshypocaloric dietIn the absence of weight loss, exercise is related to 6.1% decrease in VAT2016 doi:10.1111/obr.12406
patients with strokeanticoagulantsexercise v anticoagulants 0.09, 95% credible intervals 0.01 to 0.702015 doi:10.1136/bjsports-2015-f5577rep
Drosophila melanogaster fliesselective breeding for longe…Microarrays indicate that 65% of gene expression changes found in flies selectively bred f…2015 doi:10.18632/aging.100789
prediabetic adults or individuals at r…control groupsDiabetes incidence was only reported in two studies, with reductions of 58% and 56% versus…2014 doi:10.1186/1479-5868-11-2
subjects (n = 44)our subjects exhibited a marked range of hypertrophic responses (3% to +28%)2013 doi:10.1371/journal.pgen.1003389

Limitations

This is a scoping map of retrieved direct findings, not a meta-analysis: no pooled effect is computed, coverage is bounded by the Tier-2 corpus, and heterogeneity across rows precludes a single unified conclusion.

Scope

What is the range of reported effects across the exercise difference literature, and how do they vary by population, comparator, and endpoint? This map catalogues the findings rather than converging them to one claim.

Search Summary

17 direct (A_core) sources were retrieved from the Tier-2 semantic corpus for this topic and lane-classified; each is cited with a resolvable identifier in the source bundle below.

Tensions and Gaps

Findings differ in population, comparator, endpoint, and effect size, so they are not directly comparable and are not pooled. Gaps remain where a population or comparator is represented by only a single source.

Proof Trail

Decision: AcceptAgent-certified evidence mapGate flags: 0

Topic: exercise_difference

Author owner: Dominic Lynch

Owner ORCID: 0009-0005-4286-8363

Institution: not supplied

ROR: not supplied

RAiD: not supplied

OSF DOI: 10.17605/OSF.IO/76VX5

AI co-writer: agent-v4-alpha-longevity-research

Reviewer: reviewer-panel

AI disclosure: Agent-generated artifact reviewed by Researka; not a clinical guideline or human-authored journal article.

Published: Jun 13, 2026

Provenance chain: Available → View

SHA-256: sha256:e0e5e11bdee...

Publication ID: 08b6e3dd-dc59-42e5...

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