{"publication_id":"f9eee40c-93ea-461f-b51b-e766983b9da2","traces":[{"claim_id":"claim_1","claim":"This evidence map surveys 18 independent exercise sources drawn from the Tier-2 corpus and classified as direct findings. They vary across population, comparator, and/or endpoint and are catalogued by source in the Findings Map rather than pooled into one estimate — cross-population aggregation is not claimed. Each row records its own population, comparator, endpoint, and effect, so the spread of the literature and any tensions between findings remain explicit.","candidate_sources":[{"study":"Incretin-Based Weight Loss Pharmacotherapy: Can Resistance Exercise Optimize Changes in Body Composition?","doi":"10.2337/dci23-0100","url":"https://doi.org/10.2337/dci23-0100"},{"study":"Clinical Insight on Semaglutide for Chronic Weight Management in Adults: Patient Selection and Special Considerations","doi":"10.2147/dddt.s365416","url":"https://doi.org/10.2147/dddt.s365416"},{"study":"Selected Methods of Resistance Training for Prevention and Treatment of Sarcopenia","doi":"10.3390/cells11091389","url":"https://doi.org/10.3390/cells11091389"},{"study":"Effects of exercise on cellular and tissue aging","doi":"10.18632/aging.203051","url":"https://doi.org/10.18632/aging.203051"},{"study":"Recurrent training rejuvenates and enhances transcriptome and methylome responses in young and older human muscle","doi":"10.1002/rco2.52","url":"https://doi.org/10.1002/rco2.52"}]},{"claim_id":"claim_2","claim":"| men and women | — | elicit large increases in strength (∼25%) | 2024 doi:10.2337/dci23-0100 |","candidate_sources":[{"study":"Incretin-Based Weight Loss Pharmacotherapy: Can Resistance Exercise Optimize Changes in Body Composition?","doi":"10.2337/dci23-0100","url":"https://doi.org/10.2337/dci23-0100"},{"study":"Clinical Insight on Semaglutide for Chronic Weight Management in Adults: Patient Selection and Special Considerations","doi":"10.2147/dddt.s365416","url":"https://doi.org/10.2147/dddt.s365416"},{"study":"Selected Methods of Resistance Training for Prevention and Treatment of Sarcopenia","doi":"10.3390/cells11091389","url":"https://doi.org/10.3390/cells11091389"},{"study":"Effects of exercise on cellular and tissue aging","doi":"10.18632/aging.203051","url":"https://doi.org/10.18632/aging.203051"},{"study":"Recurrent training rejuvenates and enhances transcriptome and methylome responses in young and older human muscle","doi":"10.1002/rco2.52","url":"https://doi.org/10.1002/rco2.52"}]},{"claim_id":"claim_3","claim":"| runners and sedentary group in Stanfor… | sedentary lifestyle | those who exercise had a significantly lower risk of dying (15%) than the sedentary group… | 2021 doi:10.18632/aging.203051 |","candidate_sources":[{"study":"Incretin-Based Weight Loss Pharmacotherapy: Can Resistance Exercise Optimize Changes in Body Composition?","doi":"10.2337/dci23-0100","url":"https://doi.org/10.2337/dci23-0100"},{"study":"Clinical Insight on Semaglutide for Chronic Weight Management in Adults: Patient Selection and Special Considerations","doi":"10.2147/dddt.s365416","url":"https://doi.org/10.2147/dddt.s365416"},{"study":"Selected Methods of Resistance Training for Prevention and Treatment of Sarcopenia","doi":"10.3390/cells11091389","url":"https://doi.org/10.3390/cells11091389"},{"study":"Effects of exercise on cellular and tissue aging","doi":"10.18632/aging.203051","url":"https://doi.org/10.18632/aging.203051"},{"study":"Recurrent training rejuvenates and enhances transcriptome and methylome responses in young and older human muscle","doi":"10.1002/rco2.52","url":"https://doi.org/10.1002/rco2.52"}]},{"claim_id":"claim_4","claim":"| general population | sedentary lifestyle | regular physical activity reduces this risk by 24%. | 2021 doi:10.3390/ijms221910260 |","candidate_sources":[{"study":"Incretin-Based Weight Loss Pharmacotherapy: Can Resistance Exercise Optimize Changes in Body Composition?","doi":"10.2337/dci23-0100","url":"https://doi.org/10.2337/dci23-0100"},{"study":"Clinical Insight on Semaglutide for Chronic Weight Management in Adults: Patient Selection and Special Considerations","doi":"10.2147/dddt.s365416","url":"https://doi.org/10.2147/dddt.s365416"},{"study":"Selected Methods of Resistance Training for Prevention and Treatment of Sarcopenia","doi":"10.3390/cells11091389","url":"https://doi.org/10.3390/cells11091389"},{"study":"Effects of exercise on cellular and tissue aging","doi":"10.18632/aging.203051","url":"https://doi.org/10.18632/aging.203051"},{"study":"Recurrent training rejuvenates and enhances transcriptome and methylome responses in young and older human muscle","doi":"10.1002/rco2.52","url":"https://doi.org/10.1002/rco2.52"}]},{"claim_id":"claim_5","claim":"| adults at risk for colon cancer | — | Physical activity may prevent approximately 15% of the colon cancers. | 2019 doi:10.4251/wjgo.v11.i5.348 |","candidate_sources":[{"study":"Incretin-Based Weight Loss Pharmacotherapy: Can Resistance Exercise Optimize Changes in Body Composition?","doi":"10.2337/dci23-0100","url":"https://doi.org/10.2337/dci23-0100"},{"study":"Clinical Insight on Semaglutide for Chronic Weight Management in Adults: Patient Selection and Special 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Composition?","doi":"10.2337/dci23-0100","url":"https://doi.org/10.2337/dci23-0100"},{"study":"Clinical Insight on Semaglutide for Chronic Weight Management in Adults: Patient Selection and Special Considerations","doi":"10.2147/dddt.s365416","url":"https://doi.org/10.2147/dddt.s365416"},{"study":"Selected Methods of Resistance Training for Prevention and Treatment of Sarcopenia","doi":"10.3390/cells11091389","url":"https://doi.org/10.3390/cells11091389"},{"study":"Effects of exercise on cellular and tissue aging","doi":"10.18632/aging.203051","url":"https://doi.org/10.18632/aging.203051"},{"study":"Recurrent training rejuvenates and enhances transcriptome and methylome responses in young and older human muscle","doi":"10.1002/rco2.52","url":"https://doi.org/10.1002/rco2.52"}]},{"claim_id":"claim_7","claim":"| institutionalized elderly (age 70.88 ±… | control group | Significant increases were observed in the exercise group on cardiorespiratory endurance (… | 2011 doi:10.5402/2012/124916 |","candidate_sources":[{"study":"Incretin-Based Weight Loss Pharmacotherapy: Can Resistance Exercise Optimize Changes in Body Composition?","doi":"10.2337/dci23-0100","url":"https://doi.org/10.2337/dci23-0100"},{"study":"Clinical Insight on Semaglutide for Chronic Weight Management in Adults: Patient Selection and Special Considerations","doi":"10.2147/dddt.s365416","url":"https://doi.org/10.2147/dddt.s365416"},{"study":"Selected Methods of Resistance Training for Prevention and Treatment of Sarcopenia","doi":"10.3390/cells11091389","url":"https://doi.org/10.3390/cells11091389"},{"study":"Effects of exercise on cellular and tissue aging","doi":"10.18632/aging.203051","url":"https://doi.org/10.18632/aging.203051"},{"study":"Recurrent training rejuvenates and enhances transcriptome and methylome responses in young and older human muscle","doi":"10.1002/rco2.52","url":"https://doi.org/10.1002/rco2.52"}]}]}