{"publication_id":"f7aceb24-5650-43e9-8e4f-c8d8c3a376dd","method_note":"Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.","sources":[{"study":"Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence","doi":"10.1111/acel.14060","risk_of_bias":"not appraised in public sidecar","directness":"primary"},{"study":"Antiproliferative Mechanisms of the Flavonoids 2,2′-Dihydroxychalcone and Fisetin in Human Prostate Cancer Cells","doi":"10.1080/01635581003605524","risk_of_bias":"not appraised in public sidecar","directness":"primary"},{"study":"&lt;p&gt;Antiviral and immunomodulatory effects of polyphenols on macrophages infected with dengue virus serotypes 2 and 3 enhanced or not with antibodies&lt;/p&gt;","doi":"10.2147/idr.s210890","risk_of_bias":"not appraised in public sidecar","directness":"primary"},{"study":"Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammation","doi":"10.3389/fimmu.2022.1075804","risk_of_bias":"not appraised in public sidecar","directness":"primary"},{"study":"Fisetin, a 3,7,3′,4′-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models","doi":"10.3390/cells8091089","risk_of_bias":"not appraised in public sidecar","directness":"primary"}]}