{"publication_id":"bde27e52-8cfd-4e9f-8721-e899352f3a58","screening":{"identified":5,"screened":5,"excluded":0,"included":5,"included_or_retained":5,"flow":["identified","screened","excluded_with_reasons","included"],"wording":"5 candidate receipts retained after source retrieval, deduplication, and topic filtering. This is an evidence-map screening trace, not a PRISMA full-text exclusion audit.","exclusion_reasons":["No PRISMA full-text exclusion-stage filter was applied."]},"limitations":["This is an agent-assisted alpha memo, not a PRISMA-complete systematic review or clinical guideline.","It is not PROSPERO-registered and should not be read as medical advice.","Public sidecars expose citation traces and extraction status; empty fields mean not extracted, not assumed absent."],"contradictions":["This receipt-backed scoping note has one bounded signal: acarbose shows endpoint-specific favorable signals with context limits across this 5-source primary bundle (2012-2019). Evidence role grouping: direction-bearing receipts: 3; null/mixed metric-scope caveat receipts: 0; context/antecedent/model receipts: 2 excluded from effect support. The source facts cover 5 population/setting context(s) and 3 intervention/exposure context(s), so this is a scoping signal about where endpoints diverge, without establishing a causal, clinical, species-translated, or mechanistically integrated claim. The listed effect sizes remain source-specific across endpoints and populations; they are not pooled or averaged. This is a heterogeneous indication/context map, not a unified disease-specific or endpoint-family claim. Concrete contrast: other/mixed: Life-span Extension Drug Interventions Affect Adipose Tissue Inflammation in Aging: acarbose and 17-α estradiol do not strongly alter these phenotypes; directionally favorable: Acarbose improves health and lifespan in aging HET3 mice: significantly increased (3%) in females only at 1,000 ppm.","null/non-convergent or other/mixed: the extracted fact is null, mixed, or not directionally interpretable.","Evidence role summary: direction-bearing receipts: 3; null/mixed metric-scope caveat receipts: 0; context/antecedent/model receipts: 2 excluded from effect support."]}