{"publication_id":"b64e5dda-0774-44b5-8adf-3bb0219db815","content_hash":"sha256:47280747ae0a51552080f1051ed511940862a41d5aea8aa264aa13a75b707475","nodes":[{"id":"b64e5dda-0774-44b5-8adf-3bb0219db815","type":"publication","title":"Alpha memo: taurine supplementation"},{"id":"claim_1","type":"claim","text":"One-sentence alpha:** Receipt 1 suggests taurine supplementation can blunt a cardio-metabolic risk factor (triglycerides) in high-caloric-fed Wistar rats, while Receipt 2 reframes taurine not as a one-way aid but as a biomarker whose deficiency may signal ageing, making the same molecule read as intervention in one context and as readout in another."},{"id":"claim_2","type":"claim","text":"Receipt 1:** Effects of physical exercise and taurine supplementation on cardio‐metabolic risk factors in high caloric‐fed rats (2012) — in male Wistar rats on a 4-week high-caloric diet followed by 5 weeks of treadmill training (20 m/min, 60 min, 3×/week) and/or 2% taurine in drinking water, exercise or taurine per se reduced triglycerides, alongside an ~45% performance gain in trained groups."},{"id":"source_1","type":"source","study":"Effects of physical exercise and taurine supplementation on cardio‐metabolic risk factors in high caloric‐fed rats","year":2012,"doi":"10.1096/fasebj.26.1_supplement.1142.41","url":"https://doi.org/10.1096/fasebj.26.1_supplement.1142.41","population":"not extracted","intervention_or_exposure":"not extracted","comparator":"not extracted","endpoint":"not extracted","effect":"not extracted","risk_of_bias":"not appraised in public sidecar","directness":"primary"},{"id":"source_2","type":"source","study":"Taurine as a biomarker for aging: A new avenue for translational research","year":2023,"doi":"10.1016/j.abst.2023.10.002","url":"https://doi.org/10.1016/j.abst.2023.10.002","population":"not extracted","intervention_or_exposure":"not extracted","comparator":"not extracted","endpoint":"not extracted","effect":"not extracted","risk_of_bias":"not appraised in public sidecar","directness":"primary"}],"edges":[{"from":"b64e5dda-0774-44b5-8adf-3bb0219db815","to":"claim_1","type":"contains_claim"},{"from":"b64e5dda-0774-44b5-8adf-3bb0219db815","to":"claim_2","type":"contains_claim"}],"screening":{"identified":2,"screened":2,"excluded":0,"included":2,"included_or_retained":2,"flow":["identified","screened","excluded_with_reasons","included"],"wording":"2 candidate receipts retained after source retrieval, deduplication, and topic filtering. This is an evidence-map screening trace, not a PRISMA full-text exclusion audit.","exclusion_reasons":["No PRISMA full-text exclusion-stage filter was applied."]}}