{"publication_id":"b64067ab-fff7-4920-b478-43d193aadc87","traces":[{"claim_id":"claim_1","claim":"One-sentence alpha:** resveratrol / exercise does not carry one stable direction across the two receipts; the supported alpha is an endpoint- and setting-bounded comparison rather than a universal benefit or harm claim.","candidate_sources":[{"source_id":"source_1","study":"Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats","doi":"10.1113/jphysiol.2012.230490","url":"https://www.semanticscholar.org/paper/55611be306e3abdce30150fde45b4fc327435317","support_kind":"candidate_source_row","population":"not extracted","endpoint":"not extracted","effect":"not extracted","directness":"primary"},{"source_id":"source_2","study":"Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men","doi":"10.1113/jphysiol.2013.270256","url":"https://doi.org/10.1113/jphysiol.2013.270256","support_kind":"candidate_source_row","population":"not extracted","endpoint":"not extracted","effect":"not extracted","directness":"primary"}]},{"claim_id":"claim_2","claim":"Synthesis:** Receipt 1 reports Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats in an animal model. Receipt 2 reports Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men; excerpt: Exercise training increased skeletal muscle peroxisome proliferator-activated receptor-γ co-activator-1α mRNA ~1.5-fold, cytochrome c protein ~1.3-fold, cytochrome c oxidase I protein ~1.5-fold, citrate synthase activity ~1.3-fold, 3-hydrox in a human study. The comparison is bounded to resveratrol / exercise, and should not be read as advice, settled science, or a broad class claim.","candidate_sources":[{"source_id":"source_1","study":"Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats","doi":"10.1113/jphysiol.2012.230490","url":"https://www.semanticscholar.org/paper/55611be306e3abdce30150fde45b4fc327435317","support_kind":"candidate_source_row","population":"not extracted","endpoint":"not extracted","effect":"not extracted","directness":"primary"},{"source_id":"source_2","study":"Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men","doi":"10.1113/jphysiol.2013.270256","url":"https://doi.org/10.1113/jphysiol.2013.270256","support_kind":"candidate_source_row","population":"not extracted","endpoint":"not extracted","effect":"not extracted","directness":"primary"}]},{"claim_id":"claim_3","claim":"Interpretation:** The supported claim is not universal failure; it is that the Receipt 1 signal does not automatically transfer to the Receipt 2 population, modality, and endpoint bundle.","candidate_sources":[{"source_id":"source_1","study":"Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats","doi":"10.1113/jphysiol.2012.230490","url":"https://www.semanticscholar.org/paper/55611be306e3abdce30150fde45b4fc327435317","support_kind":"candidate_source_row","population":"not extracted","endpoint":"not extracted","effect":"not extracted","directness":"primary"},{"source_id":"source_2","study":"Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men","doi":"10.1113/jphysiol.2013.270256","url":"https://doi.org/10.1113/jphysiol.2013.270256","support_kind":"candidate_source_row","population":"not extracted","endpoint":"not extracted","effect":"not extracted","directness":"primary"}]},{"claim_id":"claim_4","claim":"Evidence gap:** The missing study is one matched design with the same population, protocol, dose, duration, and endpoint.","candidate_sources":[{"source_id":"source_1","study":"Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats","doi":"10.1113/jphysiol.2012.230490","url":"https://www.semanticscholar.org/paper/55611be306e3abdce30150fde45b4fc327435317","support_kind":"candidate_source_row","population":"not extracted","endpoint":"not extracted","effect":"not extracted","directness":"primary"},{"source_id":"source_2","study":"Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men","doi":"10.1113/jphysiol.2013.270256","url":"https://doi.org/10.1113/jphysiol.2013.270256","support_kind":"candidate_source_row","population":"not extracted","endpoint":"not extracted","effect":"not extracted","directness":"primary"}]}]}