{"publication_id":"a0900cba-0a00-4208-88a9-1b1711cbdbd3","content_hash":"sha256:0260935905d352af50f081f52564b44126cbd3ca22eede5fc632e24eb82c2041","nodes":[{"id":"a0900cba-0a00-4208-88a9-1b1711cbdbd3","type":"publication","title":"caffeine / during / exercise"},{"id":"claim_1","type":"claim","text":"Two 1991 caffeine studies appear to disagree when bundled together: a 60-minute submaximal metabolism trial showed no measurable effect, while an elite distance runner time-to-exhaustion trial at the same approximate era showed longer run distance with caffeine. The receipts support treating this as a boundary-condition tension, not a contradiction on the same metric."},{"id":"claim_2","type":"claim","text":"For elite endurance, where time-to-exhaustion is the operationally relevant endpoint, the positive-signal receipt suggests caffeine ingested just prior to exercise can extend work capacity. For submaximal steady-state work under the null-signal receipt's design, the metabolic readout does not change. The actionable read is that caffeine's lever may depend on the proximity to exhaustion rather than on average metabolism."},{"id":"claim_3","type":"claim","text":"A within-subject crossover in elite distance runners that pairs time-to-exhaustion with continuous metabolic sampling (RER, FFA, lactate) across the same 10 mg·kg⁻¹ dose would resolve whether the metabolism null is real or a sensitivity-floor artifact of the 1991 submaximal design."},{"id":"claim_4","type":"claim","text":"10.1080/02640419108729851 — null_signal: 200 mg caffeine, 60 min pre-exercise, 5 males, 60% MHR, no significant metabolic differences."},{"id":"source_1","type":"source","study":"Failure of caffeine to affect metabolism during 60 min submaximal exercise.","year":1991,"doi":"10.1080/02640419108729851","url":"https://doi.org/10.1080/02640419108729851","population":"not extracted","intervention_or_exposure":"not extracted","comparator":"not extracted","endpoint":"not extracted","effect":"not extracted","risk_of_bias":"not appraised in public sidecar","directness":"primary"},{"id":"source_2","type":"source","study":"Caffeine ingestion during exercise to exhaustion in elite distance runners. Revision.","year":1991,"doi":null,"url":"","population":"not extracted","intervention_or_exposure":"not extracted","comparator":"not extracted","endpoint":"not extracted","effect":"not extracted","risk_of_bias":"not appraised in public sidecar","directness":"primary"}],"edges":[{"from":"a0900cba-0a00-4208-88a9-1b1711cbdbd3","to":"claim_1","type":"contains_claim"},{"from":"a0900cba-0a00-4208-88a9-1b1711cbdbd3","to":"claim_2","type":"contains_claim"},{"from":"a0900cba-0a00-4208-88a9-1b1711cbdbd3","to":"claim_3","type":"contains_claim"},{"from":"a0900cba-0a00-4208-88a9-1b1711cbdbd3","to":"claim_4","type":"contains_claim"}],"screening":{"identified":2,"screened":2,"excluded":0,"included":2,"included_or_retained":2,"flow":["identified","screened","excluded_with_reasons","included"],"wording":"2 candidate receipts retained after source retrieval, deduplication, and topic filtering. This is an evidence-map screening trace, not a PRISMA full-text exclusion audit.","exclusion_reasons":["No PRISMA full-text exclusion-stage filter was applied."]}}