{"publication_id":"9071bd4f-9969-4a7f-85ee-ae7c64682a16","method_note":"Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.","sources":[{"study":"The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent","doi":"10.7554/elife.88080","risk_of_bias":"not appraised in public sidecar","directness":"primary"},{"study":"Altered proteome turnover and remodeling by short‐term caloric restriction or rapamycin rejuvenate the aging heart","doi":"10.1111/acel.12203","risk_of_bias":"not appraised in public sidecar","directness":"primary"},{"study":"Modulating fibroblast growth factor 21 in hyperphagic OLETF rats with daily exercise and caloric restriction.","doi":"10.1139/h2012-091","risk_of_bias":"not appraised in public sidecar","directness":"primary"},{"study":"Caloric restriction leads to high marrow adiposity and low bone mass in growing mice","doi":"10.1002/jbmr.82","risk_of_bias":"not appraised in public sidecar","directness":"primary"},{"study":"Circadian alignment of early onset caloric restriction promotes longevity in male C57BL/6J mice","doi":"10.1126/science.abk0297","risk_of_bias":"not appraised in public sidecar","directness":"primary"}]}