{"publication_id":"556ed33d-b232-4c19-a24c-849a8c2d81a6","traces":[{"claim_id":"claim_1","claim":"The direct receipts support a narrow working claim: Supplementation was associated with reduced risk of MI (relative risk [RR], 0.87; 95% CI, 0.80 to 0.96), high certainty NNT of 272; but not CVD events (RR, 0.95; 95% CI, 0.90 to 1.00). The context receipts provide source breadth and boundary checks, not independent confirmation of the lead claim.","candidate_sources":[{"study":"Effect of Omega-3 Dosage on Cardiovascular Outcomes","doi":"10.1016/j.mayocp.2020.08.034","url":null},{"study":"Effects of Omega-3 Polyunsaturated Fatty Acids on Brain Functions: A Systematic Review","doi":"10.7759/cureus.30091","url":null},{"study":"Higher ratio of plasma omega-6/omega-3 fatty acids is associated with greater risk of all-cause, cancer, and cardiovascular mortality: A population-based cohort study in UK Biobank","doi":"10.7554/elife.90132.3","url":null},{"study":"Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease","doi":"10.1002/14651858.cd003177.pub5","url":null},{"study":"The Effects of Vitamin D Supplementation on Musculoskeletal Health: The VITAL and DO-Health Trials","doi":"10.1093/gerona/glad073","url":null}]},{"claim_id":"claim_2","claim":"Interpretation note:** This is a hypothesis-generating alpha memo, not confirmatory evidence; subgroup or context-derived claims require independent replication.","candidate_sources":[{"study":"Effect of Omega-3 Dosage on Cardiovascular Outcomes","doi":"10.1016/j.mayocp.2020.08.034","url":null},{"study":"Effects of Omega-3 Polyunsaturated Fatty Acids on Brain Functions: A Systematic Review","doi":"10.7759/cureus.30091","url":null},{"study":"Higher ratio of plasma omega-6/omega-3 fatty acids is associated with greater risk of all-cause, cancer, and cardiovascular mortality: A population-based cohort study in UK Biobank","doi":"10.7554/elife.90132.3","url":null},{"study":"Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease","doi":"10.1002/14651858.cd003177.pub5","url":null},{"study":"The Effects of Vitamin D Supplementation on Musculoskeletal Health: The VITAL and DO-Health Trials","doi":"10.1093/gerona/glad073","url":null}]},{"claim_id":"claim_3","claim":"Real tension: the useful signal is narrower than the topic label. The lead receipts support the core claim, while the added A/B context receipts define where that claim may generalize, fail, or need a separate extraction.","candidate_sources":[{"study":"Effect of Omega-3 Dosage on Cardiovascular Outcomes","doi":"10.1016/j.mayocp.2020.08.034","url":null},{"study":"Effects of Omega-3 Polyunsaturated Fatty Acids on Brain Functions: A Systematic Review","doi":"10.7759/cureus.30091","url":null},{"study":"Higher ratio of plasma omega-6/omega-3 fatty acids is associated with greater risk of all-cause, cancer, and cardiovascular mortality: A population-based cohort study in UK Biobank","doi":"10.7554/elife.90132.3","url":null},{"study":"Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease","doi":"10.1002/14651858.cd003177.pub5","url":null},{"study":"The Effects of Vitamin D Supplementation on Musculoskeletal Health: The VITAL and DO-Health Trials","doi":"10.1093/gerona/glad073","url":null}]},{"claim_id":"claim_4","claim":"`fact_id=140174` (`A_core`) — Supplementation was associated with reduced risk of MI (relative risk [RR], 0.87; 95% CI, 0.80 to 0.96), high certainty NNT of 272 doi=10.1016/j.mayocp.2020.08.034","candidate_sources":[{"study":"Effect of Omega-3 Dosage on Cardiovascular Outcomes","doi":"10.1016/j.mayocp.2020.08.034","url":null},{"study":"Effects of Omega-3 Polyunsaturated Fatty Acids on Brain Functions: A Systematic Review","doi":"10.7759/cureus.30091","url":null},{"study":"Higher ratio of plasma omega-6/omega-3 fatty acids is associated with greater risk of all-cause, cancer, and cardiovascular mortality: A population-based cohort study in UK Biobank","doi":"10.7554/elife.90132.3","url":null},{"study":"Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease","doi":"10.1002/14651858.cd003177.pub5","url":null},{"study":"The Effects of Vitamin D Supplementation on Musculoskeletal Health: The VITAL and DO-Health Trials","doi":"10.1093/gerona/glad073","url":null}]},{"claim_id":"claim_5","claim":"`fact_id=1138` (`A_core`) — little or no effect of increasing LCn3 on all-cause mortality (risk ratio (RR) 0.97, 95% CI 0.93 to 1.01 doi=10.1002/14651858.cd003177.pub5","candidate_sources":[{"study":"Effect of Omega-3 Dosage on Cardiovascular Outcomes","doi":"10.1016/j.mayocp.2020.08.034","url":null},{"study":"Effects of Omega-3 Polyunsaturated Fatty Acids on Brain Functions: A Systematic Review","doi":"10.7759/cureus.30091","url":null},{"study":"Higher ratio of plasma omega-6/omega-3 fatty acids is associated with greater risk of all-cause, cancer, and cardiovascular mortality: A population-based cohort study in UK Biobank","doi":"10.7554/elife.90132.3","url":null},{"study":"Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease","doi":"10.1002/14651858.cd003177.pub5","url":null},{"study":"The Effects of Vitamin D Supplementation on Musculoskeletal Health: The VITAL and DO-Health Trials","doi":"10.1093/gerona/glad073","url":null}]},{"claim_id":"claim_6","claim":"`fact_id=178493` (`A_core`) — the 3 treatments combined showed a significant 39% decreased odds of becoming prefrail compared to the control doi=10.1093/gerona/glad073","candidate_sources":[{"study":"Effect of Omega-3 Dosage on Cardiovascular Outcomes","doi":"10.1016/j.mayocp.2020.08.034","url":null},{"study":"Effects of Omega-3 Polyunsaturated Fatty Acids on Brain Functions: A Systematic Review","doi":"10.7759/cureus.30091","url":null},{"study":"Higher ratio of plasma omega-6/omega-3 fatty acids is associated with greater risk of all-cause, cancer, and cardiovascular mortality: A population-based cohort study in UK Biobank","doi":"10.7554/elife.90132.3","url":null},{"study":"Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease","doi":"10.1002/14651858.cd003177.pub5","url":null},{"study":"The Effects of Vitamin D Supplementation on Musculoskeletal Health: The VITAL and DO-Health Trials","doi":"10.1093/gerona/glad073","url":null}]},{"claim_id":"claim_7","claim":"_Boundary evidence only; these receipts broaden source context but do not independently prove the lead claim._","candidate_sources":[{"study":"Effect of Omega-3 Dosage on Cardiovascular Outcomes","doi":"10.1016/j.mayocp.2020.08.034","url":null},{"study":"Effects of Omega-3 Polyunsaturated Fatty Acids on Brain Functions: A Systematic Review","doi":"10.7759/cureus.30091","url":null},{"study":"Higher ratio of plasma omega-6/omega-3 fatty acids is associated with greater risk of all-cause, cancer, and cardiovascular mortality: A population-based cohort study in UK Biobank","doi":"10.7554/elife.90132.3","url":null},{"study":"Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease","doi":"10.1002/14651858.cd003177.pub5","url":null},{"study":"The Effects of Vitamin D Supplementation on Musculoskeletal Health: The VITAL and DO-Health Trials","doi":"10.1093/gerona/glad073","url":null}]},{"claim_id":"claim_8","claim":"`fact_id=1138` (`A_core`) — little or no effect of increasing LCn3 on all-cause mortality (risk ratio (RR) 0.97, 95% CI 0.93 to 1.01 Source: Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease","candidate_sources":[{"study":"Effect of Omega-3 Dosage on Cardiovascular Outcomes","doi":"10.1016/j.mayocp.2020.08.034","url":null},{"study":"Effects of Omega-3 Polyunsaturated Fatty Acids on Brain Functions: A Systematic Review","doi":"10.7759/cureus.30091","url":null},{"study":"Higher ratio of plasma omega-6/omega-3 fatty acids is associated with greater risk of all-cause, cancer, and cardiovascular mortality: A population-based cohort study in UK Biobank","doi":"10.7554/elife.90132.3","url":null},{"study":"Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease","doi":"10.1002/14651858.cd003177.pub5","url":null},{"study":"The Effects of Vitamin D Supplementation on Musculoskeletal Health: The VITAL and DO-Health Trials","doi":"10.1093/gerona/glad073","url":null}]}]}