{"publication_id":"55517e8f-0869-4695-bf27-5ef15eac8e31","screening":{"identified":6,"screened":6,"excluded":0,"included":6,"included_or_retained":6,"flow":["identified","screened","excluded_with_reasons","included"],"wording":"6 candidate receipts retained after source retrieval, deduplication, and topic filtering. This is an evidence-map screening trace, not a PRISMA full-text exclusion audit.","exclusion_reasons":["No PRISMA full-text exclusion-stage filter was applied."]},"limitations":["This is an agent-assisted alpha memo, not a PRISMA-complete systematic review or clinical guideline.","It is not PROSPERO-registered and should not be read as medical advice.","Public sidecars expose citation traces and extraction status; empty fields mean not extracted, not assumed absent."],"contradictions":["approximately 40% of dementia cases worldwide could be attributable to 12 modifiable risk factors. Boundary receipts add a second constraint: Models with all Quanterix plasma analytes along with risk factors most often provided the best discrimination among amyloid PET stages (C = 0.78-0.82).","The interesting signal is where the evidence stops generalizing: the memo is not a broad topic summary, but a testable boundary condition.","`fact_id=142261` (`A_core`) — approximately 40% of dementia cases worldwide could be attributable to 12 modifiable risk factors doi=10.1111/joim.13227","`fact_id=170989` (`A_core`) — Globally, 61·0% (59·6–62·4) of deaths were attributed to the GBD 2017 risk factors. doi=10.1016/s0140-6736(19)31429-1","`fact_id=93195` (`A_core`) — 45.1% of cancer deaths (265,150 of 587,521 deaths) were attributable to evaluated risk factors. doi=10.3322/caac.21440","`fact_id=93194` (`A_core`) — an estimated 42.0% of all incident cancers (659,640 of 1570,975 cancers, excluding nonmelanoma skin cancers) were attributable to evaluated risk factors. doi=10.3322/caac.21440","_Boundary evidence only; these receipts broaden source context but do not independently prove the lead claim._"]}