{"publication_id":"3df522c5-e35c-4b1e-b34f-acfcac356e2a","traces":[{"claim_id":"claim_1","claim":"Aging-active consumer market: products marketed to 50+ exercisers as mitochondrial/anti-aging support could in principle blunt rather than boost cardiovascular return on training.","candidate_sources":[{"study":"Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha","doi":"10.1016/j.cell.2006.11.013","url":null},{"study":"Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men","doi":"10.1113/jphysiol.2013.258061","url":null}]},{"claim_id":"claim_2","claim":"Sports nutrition and supplement R&D: combining \"exercise-mimetic\" claims with high-intensity protocols warrants human evidence, not rodent extrapolation.","candidate_sources":[{"study":"Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha","doi":"10.1016/j.cell.2006.11.013","url":null},{"study":"Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men","doi":"10.1113/jphysiol.2013.258061","url":null}]},{"claim_id":"claim_3","claim":"Aged men only, n=27, 250 mg trans-resveratrol, 8 weeks, high-intensity training; transfer to other ages, sexes, doses, training types, or longer durations is unsupported by the receipts.","candidate_sources":[{"study":"Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha","doi":"10.1016/j.cell.2006.11.013","url":null},{"study":"Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men","doi":"10.1113/jphysiol.2013.258061","url":null}]},{"claim_id":"claim_4","claim":"Receipts are limited to a 2006 mouse mechanistic study and a 2013 RCT in 27 aged men. No causal claim for other populations, doses, or training types is supported.","candidate_sources":[{"study":"Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha","doi":"10.1016/j.cell.2006.11.013","url":null},{"study":"Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men","doi":"10.1113/jphysiol.2013.258061","url":null}]}]}