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Risk factors for falls among elderly persons living in the community. N Engl J Med. 1988;319(26):1701-1707._ DOI: 10.1056/NEJM198812293192604. PMID: 3205267.","doi":"10.1056/nejm198812293192604","risk_of_bias":"not appraised in public sidecar","directness":"review-level"},{"study":"**ADA 2024.** _American Diabetes Association. Standards of Care in Diabetes. Diabetes Care. 2024;47(Suppl 1)._ DOI: 10.2337/dc24-S006.","doi":"10.2337/dc24-s006","risk_of_bias":"not appraised in public sidecar","directness":"review-level"},{"study":"**Owen 2000.** _Owen MR, Doran E, Halestrap AP. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem J. 2000;348 Pt 3:607-614._ PMID: 10839993.","doi":null,"risk_of_bias":"not appraised in public sidecar","directness":"review-level"},{"study":"**Anisimov 2008.** _Anisimov VN, Berstein LM, Egormin PA, et al. Metformin slows down aging and extends life span of female SHR mice. 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