{"publication_id":"10caf93e-a09c-432c-9878-611122b4890e","traces":[{"claim_id":"claim_1","claim":"The cited receipts show an apparent collision between a positive direct signal in colorectal cancer survivors (82,220 patients from 16 observational studies) (Physical activity was consistently inversely associated with colorectal cancer morbidity and mortality outcomes, with 13%-60% estimated reductions in risk) and an opposing endpoint in breast cancer patients post-diagnosis (Recreational physical activity was not associated with breast cancer recurrence (HR = 0.97, 95% CI: 0.91-1.05)).","candidate_sources":[{"study":"Post‐diagnosis physical activity and sedentary behaviour and colorectal cancer prognosis: A Global Cancer Update Programme (<scp>CUP</scp> Global) systematic literature review and meta‐analysis","doi":"10.1002/ijc.34903","url":null},{"study":"Postdiagnosis recreational physical activity and breast cancer prognosis: Global Cancer Update Programme (<scp>CUP</scp> Global) systematic literature review and meta‐analysis","doi":"10.1002/ijc.34324","url":null},{"study":"Association between physical activity and mortality in colorectal cancer: A meta-analysis of prospective cohort studies","doi":"10.1002/ijc.28208","url":null},{"study":"Adherence to Diet and Physical Activity Cancer Prevention Guidelines and Cancer Outcomes: A Systematic Review","doi":"10.1158/1055-9965.epi-16-0121","url":null},{"study":"Behavioral Counseling to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults With Cardiovascular Risk Factors","doi":"10.1001/jama.2020.17108","url":null}]},{"claim_id":"claim_2","claim":"Interpretation note:** This is a hypothesis-generating alpha memo, not confirmatory evidence; subgroup or context-derived claims require independent replication.","candidate_sources":[{"study":"Post‐diagnosis physical activity and sedentary behaviour and colorectal cancer prognosis: A Global Cancer Update Programme (<scp>CUP</scp> Global) systematic literature review and meta‐analysis","doi":"10.1002/ijc.34903","url":null},{"study":"Postdiagnosis recreational physical activity and breast cancer prognosis: Global Cancer Update Programme (<scp>CUP</scp> Global) systematic literature review and meta‐analysis","doi":"10.1002/ijc.34324","url":null},{"study":"Association between physical activity and mortality in colorectal cancer: A meta-analysis of prospective cohort studies","doi":"10.1002/ijc.28208","url":null},{"study":"Adherence to Diet and Physical Activity Cancer Prevention Guidelines and Cancer Outcomes: A Systematic Review","doi":"10.1158/1055-9965.epi-16-0121","url":null},{"study":"Behavioral Counseling to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults With Cardiovascular Risk Factors","doi":"10.1001/jama.2020.17108","url":null}]},{"claim_id":"claim_3","claim":"`fact_id=160470` (`A_core`) — Physical activity was consistently inversely associated with colorectal cancer morbidity and mortality outcomes, with 13%-60% estimated reductions in risk. doi=10.1002/ijc.34903","candidate_sources":[{"study":"Post‐diagnosis physical activity and sedentary behaviour and colorectal cancer prognosis: A Global Cancer Update Programme (<scp>CUP</scp> Global) systematic literature review and meta‐analysis","doi":"10.1002/ijc.34903","url":null},{"study":"Postdiagnosis recreational physical activity and breast cancer prognosis: Global Cancer Update Programme (<scp>CUP</scp> Global) systematic literature review and meta‐analysis","doi":"10.1002/ijc.34324","url":null},{"study":"Association between physical activity and mortality in colorectal cancer: A meta-analysis of prospective cohort studies","doi":"10.1002/ijc.28208","url":null},{"study":"Adherence to Diet and Physical Activity Cancer Prevention Guidelines and Cancer Outcomes: A Systematic Review","doi":"10.1158/1055-9965.epi-16-0121","url":null},{"study":"Behavioral Counseling to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults With Cardiovascular Risk Factors","doi":"10.1001/jama.2020.17108","url":null}]},{"claim_id":"claim_4","claim":"`fact_id=75409` (`A_core`) — High versus low adherence to established nutrition and physical activity cancer prevention guidelines was consistently and significantly associated with decreases of 10% to 61% in overall cancer incidence and mortality. doi=10.1158/1055-9965.epi-16-0121","candidate_sources":[{"study":"Post‐diagnosis physical activity and sedentary behaviour and colorectal cancer prognosis: A Global Cancer Update Programme (<scp>CUP</scp> Global) systematic literature review and meta‐analysis","doi":"10.1002/ijc.34903","url":null},{"study":"Postdiagnosis recreational physical activity and breast cancer prognosis: Global Cancer Update Programme (<scp>CUP</scp> Global) systematic literature review and meta‐analysis","doi":"10.1002/ijc.34324","url":null},{"study":"Association between physical activity and mortality in colorectal cancer: A meta-analysis of prospective cohort studies","doi":"10.1002/ijc.28208","url":null},{"study":"Adherence to Diet and Physical Activity Cancer Prevention Guidelines and Cancer Outcomes: A Systematic Review","doi":"10.1158/1055-9965.epi-16-0121","url":null},{"study":"Behavioral Counseling to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults With Cardiovascular Risk Factors","doi":"10.1001/jama.2020.17108","url":null}]},{"claim_id":"claim_5","claim":"`fact_id=75763` (`A_core`) — Interventions were associated with a lower risk of cardiovascular events (pooled relative risk, 0.80 [95% CI, 0.73-0.87]; doi=10.1001/jama.2020.17108","candidate_sources":[{"study":"Post‐diagnosis physical activity and sedentary behaviour and colorectal cancer prognosis: A Global Cancer Update Programme (<scp>CUP</scp> Global) systematic literature review and meta‐analysis","doi":"10.1002/ijc.34903","url":null},{"study":"Postdiagnosis recreational physical activity and breast cancer prognosis: Global Cancer Update Programme (<scp>CUP</scp> Global) systematic literature review and meta‐analysis","doi":"10.1002/ijc.34324","url":null},{"study":"Association between physical activity and mortality in colorectal cancer: A meta-analysis of prospective cohort studies","doi":"10.1002/ijc.28208","url":null},{"study":"Adherence to Diet and Physical Activity Cancer Prevention Guidelines and Cancer Outcomes: A Systematic Review","doi":"10.1158/1055-9965.epi-16-0121","url":null},{"study":"Behavioral Counseling to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults With Cardiovascular Risk Factors","doi":"10.1001/jama.2020.17108","url":null}]}]}