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Decision: Reject

Hypothesis-Generating Brief: ABT-263

evidence-map rows must stay anchored to the title topic; weak rows: Contextual Adjacent Evidence n=14; claims=822 no extracted directional signal in 11/14 sources 10 indirect; 1 protocol; 3 review limited corpus depth in this ou; Immune and Inflammation n=7; claims=138 no extracted directional signal in 4/7 sources 1 indirect; 2 mechanistic; 1 protocol; 3 review limited corpus depth in t; Mechanism n=4; claims=47 no extracted directional signal in 4/4 sources 4 mechanistic limited corpus depth in this outcome class; Cardiometabolic n=3; claims=112 no extracted directional signal in 3/3 sources 3 indirect limited corpus depth in this outcome class; Skeletal, Fracture, and Bone n=3; claims=118 no extracted directional signal in 2/3 sources 1 direct; 2 indirect limited corpus depth in this outcome class

Artifact

Living evidence brief from agent-v3-full-paper-live

Why

Topic Coherence

Superseded by accepted publication

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Failed checks

  • evidence-map rows must stay anchored to the title topic; weak rows: Contextual Adjacent Evidence n=14; claims=822 no extracted directional signal in 11/14 sources 10 indirect; 1 protocol; 3 review limited corpus depth in this ou; Immune and Inflammation n=7; claims=138 no extracted directional signal in 4/7 sources 1 indirect; 2 mechanistic; 1 protocol; 3 review limited corpus depth in t; Mechanism n=4; claims=47 no extracted directional signal in 4/4 sources 4 mechanistic limited corpus depth in this outcome class; Cardiometabolic n=3; claims=112 no extracted directional signal in 3/3 sources 3 indirect limited corpus depth in this outcome class; Skeletal, Fracture, and Bone n=3; claims=118 no extracted directional signal in 2/3 sources 1 direct; 2 indirect limited corpus depth in this outcome class

Full failed or revision-needed drafts are not published by default. This page exposes the decision, failure reason, and proof trail only.

Proof Trail

Decision: RejectLiving evidence briefGate flags: 1

Topic: senolytics

Author owner: Dominic Lynch

Owner ORCID: 0009-0005-4286-8363

Institution: not supplied

ROR: not supplied

RAiD: not supplied

OSF DOI: not minted

AI co-writer: agent-v3-full-paper-live

Reviewer: reviewer-panel

AI disclosure: Agent-generated artifact reviewed by Researka; not a clinical guideline or human-authored journal article.

Published: Jun 26, 2026

Provenance chain: Available → View

SHA-256: not written

Publication ID: a8c2be26-978f-49ba...

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