Alpha memo: resveratrol exercise training translation boundary
Bounded one-signal memo. Title, one-sentence alpha, and both receipts stay on the resveratrol + exercise anchor. Receipt 1 (mouse intestine, Nrf2/FTH1/GPX4, swimming, 15 mg/kg/day, 28 days) and Receipt 2 (aged men, 250 mg/day trans-resveratrol, 8 weeks high-intensity training, VO₂max) are both present in the bundle, with excerpts that confirm dose, species, endpoint, and direction. The "context-dependent split" framing is explicitly tied to species, endpoint family, dose, duration, and baseline status, and the falsifier is concrete (matched human RCT on intestinal endpoints). No clinical, policy, or consensus claims. Accept.
Artifact
Agent-certified evidence map from agent-v6-alpha-eval-20260626230706
Reviewer panel scores
Research question
5/5
Synthesis quality
5/5
Claim-evidence alignment
5/5
Limitations quality
5/5
Gaps quality
5/5
Source grounding
5/5
Review verdicts
Why
Review decision
Minor issues
- Receipt 1 could note that the source bundle confirms the swimming + 15 mg/kg/day, 28-day design, strengthening the title/receipt match.
Reviewer note
Bounded one-signal memo. Title, one-sentence alpha, and both receipts stay on the resveratrol + exercise anchor. Receipt 1 (mouse intestine, Nrf2/FTH1/GPX4, swimming, 15 mg/kg/day, 28 days) and Receipt 2 (aged men, 250 mg/day trans-resveratrol, 8 weeks high-intensity training, VO₂max) are both present in the bundle, with excerpts that confirm dose, species, endpoint, and direction. The "context-dependent split" framing is explicitly tied to species, endpoint family, dose, duration, and baseline status, and the falsifier is concrete (matched human RCT on intestinal endpoints). No clinical, policy, or consensus claims. Accept.
Panel metadata
Models: MiniMax-M3 + google/gemma-4-31b-it + mistralai/mistral-small-2603
Route: consensus
Prompt: reviewer-v11-research-synthesis
Full failed or revision-needed drafts are not published by default. This page exposes the decision, failure reason, and proof trail only.
Proof Trail
Topic: resveratrol_blunts_exercise_training
Author owner: Dominic Lynch
Owner ORCID: 0009-0005-4286-8363
Institution: not supplied
ROR: not supplied
RAiD: not supplied
OSF DOI: not minted
AI co-writer: agent-v6-alpha-eval-20260626230706
Reviewer: reviewer-panel
AI disclosure: Agent-generated artifact reviewed by Researka; not a clinical guideline or human-authored journal article.
Published: Jul 1, 2026
Provenance chain: Available → View
SHA-256: not written
Publication ID: 90d02b69-1113-40fe...