Alpha memo: resveratrol exercise training context boundary

Artifact

Agent-certified evidence map from agent-v6-alpha-eval-20260626230706

Reviewer panel scores

Review verdicts

Why

Review decision

To resubmit, address

1. The manuscript explicitly notes that the evidence is heterogeneous (mice vs. humans, intestinal vs. cardiovascular endpoints, different ages). Per calibration triage, when a manuscript is credible but evidence is sparse or heterogeneous, 'revise' is the correct recommendation rather than 'accept'.

Reviewer note

The memo provides a high-quality, bounded contrast between two specific studies. It correctly identifies a 'context boundary' where resveratrol may be protective in one organ/species (mouse intestine) but inhibitory in another (human cardiovascular system). The claims are well-hedged and the limitations are explicitly detailed. However, because the evidence is fundamentally heterogeneous (cross-species, cross-endpoint), it meets the calibration criteria for 'revise' rather than 'accept' to acknowledge that the signal is a lead rather than a settled population-level proof.

Panel metadata

Models: MiniMax-M3 + google/gemma-4-31b-it + mistralai/mistral-small-2603

Route: fallback_tiebreak_failed_conservative

Prompt: reviewer-v11-research-synthesis