CLAIM CARDS
Claim Cards
Atomic claims extracted from accepted Researka artifacts, with source support, contradiction state, and provenance links when available.
Filtered to publication 55517e8f-0869-4695-bf27-5ef15eac8e31
exploratory
approximately 40% of dementia cases worldwide could be attributable to 12 modifiable risk factors. Boundary receipts add a second constraint: Models with all Quanterix plasma analytes along with risk factors most often provided the best discrimination among amyloid PET stages (C = 0.78-0.82).
Contradiction: none
Sources: 5
exploratoryInterpretation note:** This is a hypothesis-generating alpha memo, not confirmatory evidence; subgroup or context-derived claims require independent replication.
Contradiction: none
Sources: 5
exploratoryThe interesting signal is where the evidence stops generalizing: the memo is not a broad topic summary, but a testable boundary condition.
Contradiction: none
Sources: 5
exploratoryBounded research question:** Does the cited receipt bundle still support this bounded claim when population, endpoint, comparator, and time window are aligned?
Contradiction: none
Sources: 5
exploratory`fact_id=142261` (`A_core`) — approximately 40% of dementia cases worldwide could be attributable to 12 modifiable risk factors doi=10.1111/joim.13227
Contradiction: none
Sources: 5
exploratory`fact_id=170989` (`A_core`) — Globally, 61·0% (59·6–62·4) of deaths were attributed to the GBD 2017 risk factors. doi=10.1016/s0140-6736(19)31429-1
Contradiction: none
Sources: 5
exploratory`fact_id=177576` (`A_core`) — up to 90% of strokes might be prevented by addressing and treating ten modifiable stroke risk factors, half of which are related to lifestyle modifications. doi=10.3390/medicina60030504
Contradiction: none
Sources: 5
exploratory`fact_id=93195` (`A_core`) — 45.1% of cancer deaths (265,150 of 587,521 deaths) were attributable to evaluated risk factors. doi=10.3322/caac.21440
Contradiction: none
Sources: 5
exploratory`fact_id=93194` (`A_core`) — an estimated 42.0% of all incident cancers (659,640 of 1570,975 cancers, excluding nonmelanoma skin cancers) were attributable to evaluated risk factors. doi=10.3322/caac.21440
Contradiction: none
Sources: 5
exploratory`fact_id=98930` (`A_core`) — Prevalence of SCD increased from 3.9% among adults with no risk factors to 25.0% among those with four or more risk factors. doi=10.15585/mmwr.mm7120a2
Contradiction: none
Sources: 5
exploratory_Boundary evidence only; these receipts broaden source context but do not independently prove the lead claim._
Contradiction: none
Sources: 5
exploratory`fact_id=143088` (`B_context`) — Models with all Quanterix plasma analytes along with risk factors most often provided the best discrimination among amyloid PET stages (C = 0.78-0.82) doi=10.1093/brain/awad042
Contradiction: none
Sources: 5
exploratory`fact_id=143092` (`B_context`) — Lilly p-tau217 did not improve over a model with all Quanterix plasma analytes and risk factors (C = 0.85 versus 0.83) doi=10.1093/brain/awad042
Contradiction: none
Sources: 5
exploratory`fact_id=143092` (`B_context`) — Lilly p-tau217 did not improve over a model with all Quanterix plasma analytes and risk factors (C = 0.85 versus 0.83) Source: Predicting amyloid PET and tau PET stages with plasma biomarkers
Contradiction: none
Sources: 5