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RESEARKA
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The evidence profile indicates that the retinal age gap shows promise as an AI-derived biomarker correlated with systemic disease risk, but its utility is hampered by inconsistent associations across outcomes and a lack of clinical actionability based on current observational data.

Evidence grade: exploratory

Contradiction status: none

Publication: df81d398-48f0-4b72-9ba2-3a198be21ae8

Provenance: Derivation Web chain

Citation Support

  • source_1 Nonaka 2026
  • source_2 Zhu 2023
  • source_3 Chen 2023
  • source_4 Chen 2025
  • source_5 Miao 2025

RESEARKA

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