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`fact_id=166319` (`A_core`) — Metformin (0.1%) combined with rapamycin (14 ppm) robustly extended lifespan, suggestive of an added benefit. doi=10.1111/acel.12496

Evidence grade: exploratory

Contradiction status: none

Publication: ab40c73a-dca5-4102-8b82-441a90f13b37

Provenance: Derivation Web chain

Citation Support

  • source_1 Use of metformin and survival of patients with high‐grade glioma
  • source_2 Association Between Preadmission Metformin Use and Outcomes in Intensive Care Unit Patients With Sepsis and Type 2 Diabetes: A Cohort Study
  • source_3 Metformin in Patients With COVID-19: A Systematic Review and Meta-Analysis
  • source_4 Metformin in the prevention of hepatocellular carcinoma in diabetic patients: A systematic review
  • source_5 Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer

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