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Quantitative findings from this pilot trial must be interpreted with caution given its small sample size and exploratory design. The study enrolled 60 participants, a number insufficient for definitive efficacy conclusions but adequate for mechanistic proof-of-concept. Detailed effect sizes, p-values, and confidence intervals for inflammatory biomarker endpoints are presented in the evidence synthesis (Per-Study Endpoint Evidence). The absence of large-scale RCTs or cohort studies with hard inflammatory endpoints means the quantitative signal remains preliminary.

Evidence grade: exploratory

Contradiction status: none

Publication: 4753c82f-24d3-490c-8a23-6cc8d4194c24

Provenance: Derivation Web chain

Citation Support

  • source_1 Ma 2025
  • source_2 Schwartz 2021
  • source_3 Lehrke 2024
  • source_4 Imran 2023
  • source_5 Faraidy 2023

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