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Within-corpus tensions emerge between studies reporting null or non-significant findings and those demonstrating significant cardiometabolic benefits. Ozdemir 2025 demonstrated significant metabolic improvements (P = 0.001) that contrast with the null findings from observational studies. These disagreements suggest that carnosine's cardiometabolic effects are context-dependent, with intervention type, population, and endpoint specificity moderating the observed effects.

Evidence grade: exploratory

Contradiction status: none

Publication: 9f7abff5-de87-4959-b080-10eac9863ba7

Provenance: Derivation Web chain

Citation Support

  • source_1 Movahedian 2025
  • source_2 Kopytek 2025
  • source_3 Kabthymer 2024
  • source_4 Li 2025
  • source_5 Dahlen 2025

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