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Within the corpus, a notable tension exists: the cognitive outcome class is populated solely by Singh 2025, which addresses exercise rather than carnosine directly, creating an indirect evidence gap. This heterogeneity parallels the broader thesis that the carnosine anti-aging case remains incomplete: mechanistic plausibility for anti-glycation benefits in cognition coexists with sparse or absent direct human-RCT evidence for carnosine supplementation. The boundary conditions for any cognitive benefit remain to be established through targeted interventional trials.

Evidence grade: exploratory

Contradiction status: none

Publication: 9f7abff5-de87-4959-b080-10eac9863ba7

Provenance: Derivation Web chain

Citation Support

  • source_1 Movahedian 2025
  • source_2 Kopytek 2025
  • source_3 Kabthymer 2024
  • source_4 Li 2025
  • source_5 Dahlen 2025

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