CLAIM CARD
The concept of 'retinal age'—a biological age estimate derived from fundus photographs via artificial intelligence—has emerged as a potential non-invasive biomarker for systemic aging and disease risk, yet the consistency and clinical meaning of the 'retinal age gap' (predicted minus chronological age) across different outcomes remains uncertain.
Evidence grade: exploratory
Contradiction status: none
Publication: df81d398-48f0-4b72-9ba2-3a198be21ae8
Provenance: Derivation Web chain
Citation Support
source_1Nonaka 2026source_2Zhu 2023source_3Chen 2023source_4Chen 2025source_5Miao 2025