RESEARKA

Mechanistically, these findings support the notion that grip strength indexes broader neuromuscular and metabolic health. Chan 2022 documented parallel age-related declines in HGS and limb muscle mass, consistent with sarcopenia as the substrate linking grip weakness to adverse outcomes. Najjar 2026 demonstrated that segmental bioimpedance—reflecting tissue composition—improves prediction of HGS, reinforcing its biologic grounding in lean mass. Yldz 2026 showed that HGS responds to nutritional repletion, suggesting it is a dynamic rather than a fixed marker. Urbano 2026 provided functional data analysis of time-dependent HGS curves, identifying sex-based differences in neuromuscular activation patterns among older adults, which may mediate differential aging trajectories.

Citation Support

• source_1 Jayanama 2022
• source_2 TurBoned 2026
• source_3 Karahan 2026
• source_4 Cui 2021
• source_5 Aksoy 2026