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Across the retained sources, positive signals cluster around the frailty, safety and comorbidity and immune and inflammation outcome classes; null signals around the contextual adjacent evidence, cardiometabolic and deficiency prevalence outcome classes; and negative or adverse signals around the contextual adjacent evidence and cardiometabolic outcome classes. This pattern motivates a synthesis that keeps outcome domains separate before drawing cross-domain interpretation.

Evidence grade: exploratory

Contradiction status: none

Publication: 9f7abff5-de87-4959-b080-10eac9863ba7

Provenance: Derivation Web chain

Citation Support

  • source_1 Movahedian 2025
  • source_2 Kopytek 2025
  • source_3 Kabthymer 2024
  • source_4 Li 2025
  • source_5 Dahlen 2025

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